Penikanix®

Sterile powder for injectable suspension

Therapeutically classification: Antibiotic

Composition: Each vial contains:

Target species: Cattle, Horses, Sheep, Goats, Dogs and Cats

Indication:

Penikanix^® is for treatment of infections caused by bacteria sensitive to Penicillin or Kanamycin such as omphalitis, arthritis, gastrointestinal infections, respiratory tract infections, listeriosis, meningitis, mastitis, urogenital tract infection, anthrax, tetanus, malignant edema, botulism, strangles, gas gangrene, foot rot, leptospirosis, salmonellosis, actinomycosis, preoperative treatments and the control of secondary bacterial invaders in disease of viral origin.

Mechanism of action:

Penicillin is an antibiotic of the ß-lactam class and kanamycin belongs to the aminoglycosides. Penicillin acts by interfering with the formation of the bacteria cell wall while it is growing and weakens the cell wall and kills the bacteria. Penicillin G is active against many gram-positive and a limited number of gram-negative bacteria however not active against the penicillinase-producing bacteria. Aminoglycosides display bactericidal activity against most gram-negative bacteria, but not against gram-negative anaerobes and most gram-positive bacteria. This bactericidal activity is done by inhibiting protein synthesis. The combination of penicillin G procaine and Kanamycin acts synergistically and it is active against both gram-positive and gram-negative bacteria.

Dosage & Administration:

Add 10-15 ml sterile WFI to the powder, shake well then use deep intramuscular injection immediately. 

Cattle and Horses: 3000-10000 IU/kg BW penicillin G procaine and 3-10 mg/kg BW kanamycin every 24 hours.

Sheep and goats: 5000-10000 IU/kg BW penicillin G procaine and 5-10 mg/kg BW kanamycin every 24 hours

Cats and dogs: 10000-20000 IU/kg BW penicillin G procaine and 10-20 mg/kg BW kanamycin every 24 hours.

Withdrawal time:

Milk: 3 days after the last treatment

Meat: 10 days after the last treatment

Contra-indications:

Do not administer IV and SC injections.

Do not use in animals with hypersensitivity to Penicillin G Procaine and/or aminoglycosides.

Do not administer in animals with a history of severe kidney disease and hepatic function.

Do not administer concurrently with tetracycline, chloramphenicol, macrolides, lincosamide and furosemide.

Because of the possibility of procaine positive doping test, do not use penicillin G procaine, 2 weeks before racing.

Caution:

Epinephrine and antihistamines should be used immediately in case of hypersensitivity to penicillin.

Keep out of reach and sight of children.

Use only under the prescription of a veterinarian.

Storage:

Do not store above 25 °C, keep away from light and moisture.

Packing:

25×20 ml flip off-capped vials in a box

For veterinary use only