Bay Floxin®

Sterile injectable solution

Therapeutically classification: Antibiotic and NSAIDs

Composition: Each ml contains:

Florfenicol                                  300 mg

Flunixin (meglumine)                16.5 mg

Target species: Cattle

Indications:

Bay Floxin^® is used for the control and treatment of infectious disease caused by susceptible organisms to florfenicol, especially in cases of infection associated with pain, inflammation and fever, and also used for treatment of respiratory infections (BRD) caused by Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, Mycoplasma bovis and fever due to BRD.

Mechanism of action:

Florfenicol is a synthetic broad-spectrum antibiotic and bacteriostatic that is effective against most gram-positive and gram-negative bacteria. Florfenicol is a fluorinated derivative of chloramphenicol, it inhibits protein synthesis by binding to 50S ribosomal subunits. Florfenicol unlike chloramphenicol, does not increase the risk of aplastic anemia in humans and may also affect some chloramphenicol-resistant bacteria.

Flunixin meglumine is a non-steroidal anti-inflammatory drug that prevents the synthesis of prostaglandins and thromboxanes by inhibiting the cyclooxygenase enzyme and thereby exerts its analgesic, anti-inflammatory, anti-endotoxin and antipyretic activity.

Dosage & Administration:

2 ml/15 kg B.W. (40 mg florfenicol and 2.2 mg flunixin/kg B.W.), by Single dose as SC injection only in the neck

Maximum volume per injection site is 10 ml, if more than 10 ml or concurrent treatment is necessary, use a separate injection site.

Withdrawal time:

Meat: 38 days after the last treatment

Contra-indications:

Do not use in cattle that produce milk for human consumption, even in dry period.

Do not use in cattle older than 20 months due to proximity to lactation.

Do not use in animals suffering from cardiac, hepatic and renal diseases.

Do not use if there is a risk of gastrointestinal bleeding or in cases where there is evidence of altered homeostasis.

Concurrent administration of potentially nephrotoxic drugs should be avoided.

Do not use in the case of known hypersensitivity to active substances or to any of the excipients.

Caution:

Avoid use in dehydrated, hypovolemic or hypotensive animals as there is a potential risk of increased renal toxicity.

The product should be used with caution in the pre-ruminant calves because repeated daily injections can cause abomasal erosions.

Keep out of reach and sight of children.

Use only under the prescription of a veterinarian.

In use stability:

28 days after first needle insertion

Storage:

Do not store above 25°C, keep away from light and freezing.

Packing:

50 ml vial in a box

For veterinary use only