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Bay Clomectin®

Bay Clomectin®

Bay Clomectin®

Sterile Injectable solution

Therapeutically classification: Antiparasite

Composition: each ml contains:

Closantel (sodium)        125 mg

Ivermectin                     5 mg

Target species: Cattle and Sheep


Bay Clomectin® is used for treatment of mixed trematode (fluke), nematode or arthropod infestations due to the following gastrointestinal roundworms, lungworms, eyeworms, warbles, mites and lice:

Trematodes (liver fluke): Fasciola hepatica and Fasciola gigantica

Gastrointestinal nematodes: Ostertagia spp., Teladorsagia spp., Haemonchus spp., Trichostrongylus spp., Cooperia spp., Oesophagostomum spp., Nematodirus spp., Strongyloides spp., Bunostomum spp., Toxocara spp. and Trichuris spp. and Chabertia spp.

Lungworms: Dictyocaulus spp. and Protostrongylus spp.

Eye worms: Thelazia spp.

Lice: Linognathus spp. and Hematopinus spp. and Solenoptes spp.

Mites: Sarcoptes spp. and Psoroptes spp.

Oestridae larvae: Hypoderma bovis, Hyporderma lineatum and Oestrus ovis

Mechanism of action:

Closantel is a synthetic antiparasitic agent, which is highly effective against liver fluke, bloodsucking nematodes and larval stages of some arthropods in cattle and sheep. Closantel decouples the mitochondrial oxidative phosphorylation, which leads to the inhibition of ATP synthesis. This causes a significant change in energy metabolism, leading to the death of the parasite.

Ivermectin is a class of macrocyclic lactone anthelmintic that enhances the release of GABA at presynaptic neurons. GABA acts as an inhibitory neurotransmitter and blocks the post-synaptic stimulation of the adjacent neuron in nematodes or the muscle fibers in arthropods. By stimulating the release of GABA and or producing a slow and irreversible increase in permeability of glutamate-gated chloride channels (GluCl) to chloride ions and hyperpolarization of nerve cells, doramectin causes flaccid paralysis of the parasite and eventual death. Tapeworms (Cestoda) and flatworms (Trematoda) (such as Fasciola species) do not use GABA as a chemical mediator in peripheral nerves, so this drug has no effect on these parasites.

Dosage & Administration:

1 ml/25 kg B.W. by SC administration

Withdrawal times:


Cattle: 49 days after the last treatment

Sheep: 28 days after the last treatment

Contra indications:

Do not use in case of hypersensitivity to the active ingredients or any of the excipients.
Do not use for IV or IM administration.
Do not use in cattle or ewes produce milk for human consumption, even in the dry period.

Do not administer concomitantly with chlorinated compounds (pesticide).

Dispose of unused products and containers by incineration or in approved-landfills.

Ivermectin is very toxic for aquatic organisms and may accumulate in sediments.

Medication recommendation:

This product can be administered to cattle and ewes at any stage of pregnancy, supposing that the milk of lactation animals should not be consumed by human.


Do not administer more than 10 ml per injection site.

Keep out of reach and sight of children.

Use only under the prescription of a veterinarian.

In use stability:

28 days after first needle insertion


Do not store above 25°C, keep away from light and freezing.


50 ml vial in a box

For veterinary use only