Therapeutic classification: Antiparasite
Composition: Each ml contains:
Target species: Cattle
Bay Dorectin® 0.5% is used for treatment of:
Gastrointestinal roundworms (adults and fourth stage larvae): Ostertagia ostertagi (inc. inhibited larvae), Haemonchus placei, Trichostrongylus axei, Cooperia oncophora, Cooperia punctate, Bunostomum phlebotomum, Oesophagostomum radiatum and Trichuris spp.
Lungworms (adults and fourth stage larvae): Dictyocaulus viviparus
Eyeworms (adults): Thelazia spp.
Warbles (parasitic stages): Hypoderma bovis and Hypoderma lineatum
Biting lice: Damalinia (Bovicola) bovis
Sucking lice: Haematopinus eurystemus, Linognathus vituli and Solenopotes capillatus
Mange mites: Psoroptes bovis, Sarcoptes scabiei and Chorioptes bovis
Horn fly: Haematobia irritans
Mechanism of action:
Doramectin is a class of macrocyclic lactone anthelmintic that enhances the release of GABA at presynaptic neurons. GABA acts as an inhibitory neurotransmitter and blocks the post-synaptic stimulation of the adjacent neuron in nematodes or the muscle fibers in arthropods. By stimulating the release of GABA and or producing a slow and irreversible increase in permeability of glutamate-gated chloride channels (GluCl) to chloride ions and hyperpolarization of nerve cells, doramectin causes flaccid paralysis of the parasite and eventual death. Tapeworms (Cestoda) and flatworms (Trematoda) (such as Fasciola species) do not use GABA as a chemical mediator in peripheral nerves, so this drug has no effect on these parasites.
Dosage & Administration:
A single treatment of 1 ml (5 mg)/10 kg B.W., applied topically along the mid-line of the back in a narrow strip between the withers and tail head.
Meat: 35 days
Do not use in cattle that produce milk for human consumption.
Doramectin is very toxic to aquatic organisms and may accumulate in sediments. The risk to aquatic ecosystem will be reduced by keeping treated cattle away from water bodies for 2 to 5 weeks after treatment.
For external use only
Should be used within 30 days after opening the seal.
Do not smoke or eat while handling the product.
Wash your hands after use.
Keep out of reach and sight of children.
Use only under the prescription of a veterinarian.
Do not store above 25 °C, keep away from light and freezing.
250 mL HDPE bottle in a box
For veterinary use only