Intramammary infusion
Therapeutic classification: Antibiotic & steroidal anti-inflammatory
Composition: Each 10 g syringe contains:
Lincomycin (HCl) | 350 | mg |
Neomycin (sulfate) | 150 | mg |
Prednisolone (acetate) | 10 | mg |
Oily base q.s. | 10 | g |
Target species: Lactating cows
Indication:
Mastolip® MC is used for treatment and control of bacterial infections caused mastitis in dairy cows during lactating period.
Mechanism of action:
Lincomycin inhibits bacterial protein synthesis and it is active against gram-positive bacteria, including Staphylococcus, Streptococcus and Mycoplasmas; however, it is rarely active against gram-negative bacteria such as E. coli and Salmonella. Neomycin has a broad-spectrum activity against both Gram-positive bacteria, including Staphylococcus and Streptococcus and gram-negative bacteria including E. coli and Salmonella spp. The combination of lincomycin and neomycin has bactericidal effect against Staphylococcus aureus and E. coli and bacteriostatic activity against Streptococcus. Glucocorticoid is an anti-inflammatory drug. Prednisolone acts to inhibit inflammatory cells and suppresses expression of inflammatory mediators. Prednisolone is approximately four times more potent than cortisol.
Dosage & Administration:
Clean and disinfect the teat, then infuse one syringe into each quarter at the last lactating. Massage the medication up into the milk cistern. If necessary, be repeated within 12 hours (up to 3 times).
Withdrawal time:
Milk: 3 days after the last treatment
Meat: 7 days after the last treatment
Contra-indications:
Do not administer to animals that are hypersensitive or resistant to lincomycin or neomycin. Use cautiously in patients with renal disease, because it may cause azotemia.
Do not use in dry cows.
Caution:
Shake well before use.
Keep out of reach and sight of children.
Use only under the prescription of a veterinarian.
Storage:
Do not store above 25°C, keep away from light and freezing.
Packing:
20×10 g syringes in a box