Aflactam® 2+1+1

Sterile powder for injectable suspension       

Therapeutically classification: Antibiotic

Composition: Each vial contains:

Target species: Cattle, horses, sheep, goats, dogs and cats

Indication:

Aflactam^® 2+1+1 exerts a bactericidal action against mainly Gram-positive bacteria like Clostridium, Campylobacter, Haemophilus, Pasteurella haemolytica, Pasteurella multocida, Corynebacterium pyogenes, Listeria, Streptococcus, Bacillus anthracis, Actinomyces bovis. It is used in the treatment of severe acute infections and when a high concentration of penicillin in the blood is needed and in the treatment of infections caused by microorganisms that are sensitive to penicillin such as Arthritis, Omphalitis, Listeriosis, Septicemia, Gastrointestinal infections, Respiratory tract infection, Urogenital tract infections, Anthrax, Tetanus, Gas gangrene,  Malignant edema,  Leptospirosis, Botulism, Strangles, preoperative treatments and secondary infection caused by penicillin sensitive micro-organims.

Mechanism of action:

Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall mucopeptide. Penicillin G is active against many gram-positive and a limited number of gram-negative bacteria however not active against the penicillinase-producing bacteria. Penicillin G benzathine is absorbed very slowly from the intramuscular injection site and converted by hydrolysis into penicillin G. Penicillin G potassium appears quickly in the blood after the intramuscular injection and penicillin G procaine is absorbed slowly after the intramuscular injection.

Dosage & Administration:

Add 15 ml sterile WFI to the powder, shake well then use deep intramuscular injection immediately.

Cattle, sheep and goats: 10000-50000 IU/kg BW

Horses: 10000-50000 IU/kg BW

Dogs and Cats: 20000-50000 IU/kg BW

Withdrawal time:

Meat: 10 days after the last treatment

Milk: 3 days after the last treatment

Contra-indications:

Do not administer IV and SC injection.

Do not use in animals with hypersensitivity to penicillin.

Do not administer concurrently with tetracyclines, florfenicol and phenylbutazone.

Because of the possibility of procaine positive doping test, do not use procaine penicillin G, 2 weeks before racing.

Caution:

Keep out of reach and sight of children.

Use only under the prescription of a veterinarian.

Storage:

Do not store above 25 °C, keep away from light and moisture.

Packing:

25×20 ml flip off-capped vials in a box.

For veterinary use only