Helmitril® 8.75%

Oral suspension

Therapeutically classification: Anthelmintic

Composition: Each ml contains:

Target species: Sheep and Goats

Indication:

Helmitril^® 8.75% is a broad-spectrum antiparasite drug, it is used for control and treatment of mature and immature forms of gastrointestinal nematodes in sheep and goats (Haemonchus spp., Cooperia spp., Nematodirus spp. etc.), mature & immature form of pulmonary worms (different species of Dictyocaulos)

Mature & immature form of gastrointestinal trematodes (Fasciola spp.)

Mechanism of action:

After oral administration, Levamisole is absorbed from intestine and spreads throughout the body. Levamisole immediately effects on the worm nervous system and causes paralysis of parasites and consequently separated them from respiratory and gastrointestinal mucosa.

Triclabendazole is belong of benzimidazole family by inhibiting the activity of fumarate reductase enzyme; it prevents the reduction of fumarate to succinate in mitochondria and prevents energy production. In the absence of usable energy the parasite dies.

Pharmacokinetic:

This drug is partly absorbed in the intestine, the peak plasma concentration occurs in 6-30 hours. Approximately 47% of an oral dose was recovered (as metabolites) in the urine over a 9 day period.

Dosage & Administration:

1 ml of suspension per 5 kg of body weight as an oral drench.

(Note: Treatment should be started at the beginning of the clinical signs in the herd.)

Withdrawal time:

Meat: 28 days after the last treatment / Milk: 7 days after the last treatment

Caution:

Shake well before use.

Wash hands after use.

This product can be safely administered to young and pregnant animals, but it used with caution in heavily pregnant and under stress or weakness condition.

The suspension must be consumed according to the correct weight and the exact dose recommendation, transient side effects such as muscle tremor, hypersalivation may occur following over dosing.

Do not administer it forcefully to animal due to incidence of aspiration pneumonia.

Should be used within 30 days after opening the seal.

Keep out of reach and sight of children.

Use under the prescription of veterinarian.

Storage:

Do not store above 25 °C, keep away from light and freezing.

Packing:

1000 ml HDPE bottle in a box

For veterinary use only