Mastapin® DC

Cloxacillin (benzathine) + Ampicillin (trihydrate)

Intramammary infusion      

Therapeutically classification: Antibiotic

Composition: Each 5 g syringe contains:

Cloxacillin (benzathine)	500	mg
Ampicillin (trihydrate)	250	mg
Oily base q.s.	5	g

Target species: Dry cows

Indications:

Mastapin^® DC is used for treatment of dairy cows at drying off, to treat existing subclinical mastitis due to penicillin resistant and sensitive Staphylococcus aureus, Streptococcus uberis, Streptococcus agalactiae, Streptococcus dysagalagtiae, Corynebacterium spp., and E. coli and prevent further infection. It also aids in reducing the incidence of summer mastitis.

Mechanism of action:

Ampicillin and cloxacillin are both beta-lactam class. In combination, ampicillin and cloxacillin have a synergistic action against a range of Gram-positive and Gram-negative bacteria. Cloxacillin binds to the β-lactamase enzyme and thus prevents the enzyme acting on ampicillin. This product is well distributed within the udder, and shows bactericidal activity at the concentrations achieved in the udder against all major Gram-positive and Gram-negative bacteria associated with mastitis, with no irritant properties.

Dosage & Administration:

Clean and disinfect the teat, then infuse one syringe into each quarter at the last lactating. Massage the medication up into the milk cistern.

Withdrawal time:

Milk: 5 days after parturition

Meat: 28 days after the last treatment

Contra-indications:

Do not use in lactating cows.

Not to be used within 45 days of calving.

Caution:

Shake well before use.

Allergic reaction to beta-lactams may occur in some animals.

Use only under the prescription of a veterinarian.

Keep out of reach and sight of children.

Storage:

Do not store above 25°C, keep away from light and freezing.

Packing:

20×5 g syringes in a box

For veterinary use only