Baymetozin^®

Sulfadiazine (sodium) + Trimethoprim

Sterile injectable suspension

Therapeutically classification: Antibiotic

Composition: Each ml contains:

Sulfadiazine (sodium)	400	mg
Trimethoprim	80	mg

Target species: Horses, Foals, Cattle, Calves and Sheep

Indications:

Baymetozin^® 48% is indicated in the treatment of respiratory tract infections with bacterial origin like rhinitis, pneumonia and bronchitis, secondary bacterial infections due to viral or mycoplasma infections. It is also indicated in urogenital tract infections such as nephritis, cystitis, urethritis, metritis and vaginitis, alimentary tract infections like neonatal diarrhea and salmonellosis. Other infections include foot rot, acute mastitis and infections of eye, ear and mouth. Baymetozin® has an excellent efficacy in anti-microbial resistance conditions, septicemia, post-operative and post-partum infections.

Mechanism of action:

Baymetozin^® 48% is a potentiated sulfonamide preparation. This product has sulfonamide in combination with trimethoprim that produce a double blockade in folic acid synthesis and prevent bacterial thymidine synthesis and is a bactericide. Consequently, greater efficacy is obtained in comparison to each component is used alone. The bactericidal spectrum of Baymetozin^® is wide and is effective on most gram-negative and gram-positive bacteria such as Streptococcus spp., Staphylococcus spp., Diplococcus spp., Enterococcus spp., Actinobacillus spp., Actinomyces spp., Salmonella spp., Pasteurella spp., Proteus spp., E. coli, Corynebacterium spp., Clostridium spp., Vibrio spp., Bordetella spp., Brucella spp., Klebsiella spp., Shigella spp. and Haemophilus spp.

Dosage & Administration:

1 ml per 30 kg B.W. (15 mg /kg B.W.), daily by intramuscular injection, preferably into neck to minimize pain.

In severe cases, this dose may be increased to 1.5 ml per 30 kg B.W. (22.5 mg /kg B.W.), daily.

A single injection usually is sufficient in cases like wounds and post-operative infections.

In severe and more complicated infections, the administration should be repeated up to 5 consecutive days or 2 doses after the clinical signs of infection are resolved.

Note: Should not be administered more than 20 ml in one site of cattle and horses body.

Withdrawal times:

Meat: 10 days after the last treatment
Milk: 3 days after the last treatment

Contra-indications:

Should not be administered intravenously and intraperitoneally.

Do not use meat and milk of animals during the treatment period with this suspension, for human consumption.

Do not use in animals with known sulfonamide sensitivity, severe liver and kidney impairment and blood dyscrasias.

Adequate drinking water should be available to the animal during the treatment period.

Do not administer to horses exhibiting drug-induced cardiac arrhythmias subsequent to taking medications like anesthetics and sedatives.

Caution:

Shake well before use.

Small swelling may be occurred at application site which withdraws fast and spontaneously.

Keep out of reach and sight of children.

Use only under the prescription of a veterinarian.

In use stability:

28 days after first needle insertion

Storage:

Do not store above 25°C, keep away from light and freezing.

Packing:

50 ml vial in a box

For veterinary use only