Sterile Injectable Solution
Therapeutically classification: Antibiotic
Composition: Each ml contains:
|Oxytetracycline (HCl) 100 mg|
Target species: Cattle, Horses, Sheep, Goats, Dogs and Cats
Oxytetracycline is a broad-spectrum bacteriostatic antibiotic. It has activity against most gram-negative and gram-positive bacteria, also it is effective against Mycoplasma, Spirochetes, Chlamydia and Rickettsia.
Cattles, Sheep & Goats:
For control and treatment of urogenital infections (e.g. metritis, mastitis, pyelonephritis and etc.), respiratory infections (e.g. pasteurellosis, pneumonia, pleurisy) and other infectious diseases (e.g. brucellosis, anthrax, foot rot, enterotoxaemia, Actinomycosis, Actinobacillosis and post-surgical infections).
Horses: Articular infections such as lyme disease, strangles, enteritis and pneumonia.
Dogs & Cats: Bartonellosis, Distemper, Feline pan-leukopenia and Kennel cough.
Mechanism of action:
Tetracyclines generally act as bacteriostatic antibiotics and inhibit protein synthesis by binding to 30S ribosomal subunits of susceptible organisms, thereby preventing binding to those ribosomes of aminoacyl transfer-RNA. Tetracyclines also are believed to reversibly bind to 50S ribosomal subunits and additionally alter cytoplasmic membrane permeability in susceptible organisms. In high concentrations, tetracyclines can also inhibit protein synthesis by mammalian cells.
After IM administration of oxytetracycline, peak levels may occur in 30 minutes to several hours, depending on the volume and site of injection. Tetracyclines as a class, are widely distributed in the body, including to heart, kidney, lungs, muscle, pleural fluid, bronchial secretion, sputum, bile, saliva, urine, synovial fluid, ascetic fluid, and aqueous and vitreous humor. Only small quantities of oxytetracycline are distributed to the CSF and therapeutic levels may not be attainable. Tetracyclines cross the placenta, enter fetal circulation and are distributed into the milk. Oxytetracycline is eliminated unchanged primarily via glomerular filtration.
Administration & Dosage:
Recommended dose is 5-10 mg/kg body weight for 4-5 days.
Or 2-5 ml / 45 kg body weight, IM, IV & SC for 4-5 days.
Cattles: 14 days after the last treatment
Sheep: 7 days after the last treatment
Milk: 5 days after the last treatment
Administer by slow IM injection and if another injection is required, use a different site for injection.
Avoid administering more than 10 ml in one site.
Intrathecal injection is very dangerous, but in case of severe infection, administer with caution.
Administer with extreme caution during the second half of pregnancy because of its effects on fetus (embryo osteogenesis disorders and discoloration of teeth).
Keep out of reach and sight of children.
Use under the prescription of a veterinarian.
Do not store above 25°C, keep away from light and freezing
In use stability:
14 days after first inject needle
50 ml vial in a box
For veterinary use only
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